Estrogen receptor alpha is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. [RefSeq]

Optimal dilution of the ER alpha antibody should be determined by the researcher.

A synthetic peptide specific to human ER alpha / ESR1 was used as the immunogen for the ER alpha antibody.

Store the ER alpha antibody at -20oC.