The neuronal migration protein Doublecortin is a microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration. [UniProt]

Optimal dilution of the Doublecortin antibody should be determined by the researcher.

A synthetic peptide specific to human Doublecortin / DCX was used as the immunogen for the Doublecortin antibody.

Store the Doublecortin antibody at -20oC.