Transcription factor SOX-6 is a protein that in humans is encoded by the SOX6 gene. This gene encodes a member of the D subfamily of sex determining region y-related transcription factors that are characterized by a conserved DNA-binding domain termed the high mobility group box and by their ability to bind the minor groove of DNA. The encoded protein is a transcriptional activator that is required for normal development of the central nervous system, chondrogenesis and maintenance of cardiac and skeletal muscle cells. The encoded protein interacts with other family members to cooperatively activate gene expression. Alternative splicing results in multiple transcript variants.

Optimal dilution of the SOX6 antibody should be determined by the researcher.

Amino acids DQDTVMKAIQEARKMREQIQREQQQQ from the human protein were used as the immunogen for the SOX6 antibody.

After reconstitution, the SOX6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.