Aciculin, also known as PGM5 (phosphoglucomutase 5) or PGMRP, is a 567 amino acid protein that belongs to the phosphoglucomutase family of phosphotransferases, which play an important role in the interconversion of glucose-1-phosphate and glucose-6-phosphate. Localized to the cell junction and expressed at high levels in smooth and cardiac muscle, Aciculin binds magnesium as a cofactor and interacts with dystrophin and utrophin, possibly playing a role in cytoskeletal organization and function. Aciculin exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome.

Optimal dilution of the Aciculin antibody should be determined by the researcher.

The cytoskeletal fraction of the human myometrium tissue extract was used as the immunogen for the Aciculin antibody.

Store the Aciculin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).