The tumor necrosis factor receptor (TNFR) superfamily represents a growing family of type I transmembrane glycoproteins that are involved in various cellular functions, including proliferation, differentiation and programmed cell death. These proteins share homology for cysteine-rich repeats in the extracellular ligand binding domain and an intracellular death domain. Members of the TNFR superfamily transmit signals through protein-protein interactions, and these signals can lead to the activation of either the caspase and Jun kinase pathways, which promote cell death, or the NFB signaling pathway.

Optimal dilution of the TNFRSF18 antibody should be determined by the researcher.

Human full-length TNFRSF18 protein was used as the immunogen for this TNFRSF18 antibody.

Store the TNFRSF18 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).