Terminal deoxynucleotidyltransferase (TdT) is a DNA polymerase which catalyzes the addition of deoxyribonucleotides onto the 3 termini of DNA. The human TdT gene maps to chromosome 10q24.1 and encodes a 510 amino acid protein. Human TdT is synthesized as a single chain peptide that elicits a minor preference for incorporation of deoxyribonucleotides over ribonucleotides forming DNA strands. It is present in immature thymocytes, some bone marrow cells, transformed pre-B and pre-T cell lines, and leukemia cells.

Optimal dilution of the TdT antibody should be determined by the researcher.

A portion of amino acids 52-192 from the human protein was used as the immunogen for the TdT antibody.

Store the TdT antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).