Napsin is a pepsin-like aspartic proteinase connected with maturation of surfactant protein B.There are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs.

Optimal dilution of the Napsin A antibody should be determined by the researcher.

Amino acids 189-299 from the human protein were used as the immunogen for the Napsin A antibody.

Store the Napsin A antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).