Integrins are heterodimers composed of noncovalently associated transmembrane both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.

Optimal dilution of the Integrin alpha V + beta 6 antibody should be determined by the researcher.

Mouse fibroblasts retrovirally infected with cDNA to express a mouse/human avb6 chimera was used as the immunogen for the Integrin alpha V + beta 6 antibody.

Store the Integrin alpha V + beta 6 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).