In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation.
The stated application concentrations are suggested starting points. Titration of the HOXA3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 413-440 from the human protein was used as the immunogen for the HOXA3 antibody.
Aliquot the HOXA3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.