Ribosomes, the organelles that catalyze protein synthesis,consist of a small 40S subunit and a large 60S subunit. Togetherthese subunits are composed of 4 RNA species and approximately 80structurally distinct proteins. This gene encodes a ribosomalprotein that is a component of the 60S subunit. The protein belongsto the L15P family of ribosomal proteins. It is located in thecytoplasm. Variable expression of this gene in colorectal cancerscompared to adjacent normal tissues has been observed, although nocorrelation between the level of expression and the severity of thedisease has been found. As is typical for genes encoding ribosomalproteins, multiple processed pseudogenes derived from this gene aredispersed through the genome.
The stated application concentrations are suggested starting points. Titration of the RPL27A antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 110-138 from the human protein was used as the immunogen for the RPL27A antibody.
Aliquot the RPL27A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
