Neurofilaments are type IV intermediate filamentheteropolymers composed of light, medium, and heavy chains.Neurofilaments comprise the axoskeleton and they functionallymaintain the neuronal caliber. They may also play a role inintracellular transport to axons and dendrites. This gene is amember of the intermediate filament family and is involved in themorphogenesis of neurons.

The stated application concentrations are suggested starting points. Titration of the Neurofilament-66 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

A portion of amino acids 290-319 from the human protein was used as the immunogen for the Neurofilament-66 antibody.

Aliquot the Neurofilament-66 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.