The protein encoded by this gene is a member of the fattyacid desaturase (FADS) gene family. Desaturase enzymes regulateunsaturation of fatty acids through the introduction of doublebonds between defined carbons of the fatty acyl chain. FADS familymembers are considered fusion products composed of an N-terminalcytochrome b5-like domain and a C-terminal multiplemembrane-spanning desaturase portion, both of which arecharacterized by conserved histidine motifs. This gene is clusteredwith family members FADS1 and FADS2 at 11q12-q13.1; this cluster isthought to have arisen evolutionarily from gene duplication basedon its similar exon/intron organization.
The stated application concentrations are suggested starting points. Titration of the FADS2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 79-108 from the human protein were used as the immunogen for the FADS2 antibody.
Aliquot the FADS2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
