This gene encodes a protein that is a member of the M49family of metallopeptidases. This cytoplasmic protein binds asingle zinc ion with its zinc-binding motif (HELLGH) and haspost-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Prodipeptides from the N-termini of proteins. Increased activity ofthis protein is associated with endometrial and ovarian cancers.Alternate transcriptional splice variants have been characterized.
The stated application concentrations are suggested starting points. Titration of the Dipeptidyl peptidase 3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 583-612 from the human protein was used as the immunogen for the Dipeptidyl peptidase 3 antibody.
Aliquot the Dipeptidyl peptidase 3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
