This gene encodes class I alcohol dehydrogenase, gammasubunit, which is a member of the alcohol dehydrogenase family.Members of this enzyme family metabolize a wide variety ofsubstrates, including ethanol, retinol, other aliphatic alcohols,hydroxysteroids, and lipid peroxidation products. Class I alcoholdehydrogenase, consisting of several homo- and heterodimers ofalpha, beta, and gamma subunits, exhibits high activity for ethanoloxidation and plays a major role in ethanol catabolism. Three genesencoding alpha, beta and gamma subunits are tandemly organized in agenomic segment as a gene cluster.
The stated application concentrations are suggested starting points. Titration of the ADH1C antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 231-260 from the human protein was used as the immunogen for the ADH1C antibody.
Aliquot the ADH1C antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
