
Sulfonation, an important step in the metabolism of many drugs, xenobiotics, hormones, and neurotransmitters, is catalyzed by sulfotransferases. GAL3ST1 is galactosylceramide sulfotransferase which catalyzes the conversion between 3"-phosphoadenylylsulfate + a galactosylceramide to adenosine 3",5"-bisphosphate + galactosylceramide sulfate. Activity of this sulfotransferase is enhanced in renal cell carcinoma.
The stated application concentrations are suggested starting points. Titration of the Galactosylceramide sulfotransferase antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 88-116 from the human protein was used as the immunogen for the Galactosylceramide sulfotransferase antibody.
Aliquot the Galactosylceramide sulfotransferase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.