
The protein encoded by this gene is a member of themitogen-activated protein kinase (MAPK) family. These familymembers function in a protein kinase signal transduction cascade,where an activated MAPK kinase kinase (MAP3K) phosphorylates andactivates a specific MAPK kinase (MAP2K), which then activates aspecific MAPK. This MAP3K protein plays an essential role inapoptotic cell death triggered by cellular stresses. [provided byRefSeq].
The stated application concentrations are suggested starting points. Titration of the MAP3K15 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 315-342 from the human protein was used as the immunogen for the MAP3K15 antibody.
Aliquot the MAP3K15 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.