This gene encodes a member of the basic helix-loop-helixleucine zipper family, and can function as a cellular transcriptionfactor. The encoded protein can activate transcription throughpyrimidine-rich initiator (Inr) elements and E-box motifs. Thisgene has been linked to familial combined hyperlipidemia (FCHL).Two transcript variants encoding distinct isoforms have beenidentified for this gene.
The stated application concentrations are suggested starting points. Titration of the Upstream stimulatory factor 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 174-201 from the human protein was used as the immunogen for the Upstream stimulatory factor 1 antibody.
Aliquot the Upstream stimulatory factor 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
