
This gene encodes multiple inositol polyphosphatephosphatase; an enzyme that removes 3-phosphate from inositolphosphate substrates. It is the only enzyme known to hydrolzyeinositol pentakisphosphate and inositol hexakisphosphate. Thisenzyme also converts 2,3 bisphosphoglycerate (2,3-BPG) to2-phosphoglycerate; an activity formerly thought to be exclusive to2,3-BPG synthase/2-phosphatase (BPGM) in the Rapoport-Lueberingshunt of the glycolytic pathway.
The stated application concentrations are suggested starting points. Titration of the MINPP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 28-55 from the human protein was used as the immunogen for the MINPP1 antibody.
Aliquot the MINPP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.