
COL5A1 encodes an alpha chain for one of the lowabundance fibrillar collagens. Fibrillar collagen molecules aretrimers that can be composed of one or more types of alpha chains.Type V collagen is found in tissues containing type I collagen andappears to regulate the assembly of heterotypic fibers composed ofboth type I and type V collagen. COL5A1 product is closelyrelated to type XI collagen and it is possible that the collagenchains of types V and XI constitute a single collagen type withtissue-specific chain combinations. Mutations in this gene areassociated with Ehlers-Danlos syndrome, types I and II. [providedby RefSeq].
The stated application concentrations are suggested starting points. Titration of the COL5A1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 54-82 from the human protein was used as the immunogen for the COL5A1 antibody.
Aliquot the COL5A1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.