Recognizes CD29. Binds to the cell membrane of T- and B- lymphocytes, monocytes, platelets, fibroblasts, endothelial cells, mast cells and smooth muscle cells. CD29 is an adhesion receptor and co-stimulatory molecule. This antigen was initially characterized as GPIIa on platelets and as the common b1 subunit of the very late antigen (VLA) protein family. CD29 forms a non-covalent heterodimeric complex with integrin alpha subunits. It also mediates adhesion to invasion and thrombospondin.

Optimal dilution of the CD29 antibody should be determined by the researcher.

Purified human beta 1 integrin from HT1080 fibrosarcoma cell extract was used as the immunogen for this CD29 antibody.

Store the CD29 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).