ATP citrate lyase, aslo known as ACLY,is anenzymethat in animals represents an important step infatty acid biosynthesis. ATP citrate lyase is the primary enzyme responsible for the synthesis ofcytosolicacetyl-CoAin many tissues. The enzyme is a tetramer of apparently identical subunits. The product, acetyl-CoA, in animals serves several important biosynthetic pathways, includinglipogenesis andcholesterogenesis.It is activated by insulin. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine.In plants, ATP citrate lyase generates the acetyl-CoA for cytosolically-synthesized metabolites.

Optimal dilution of the ATP Citrate Lyase antibody should be determined by the researcher.

A human recombinant protein (amino acids M1-I180) was used as the immunogen for the ATP Citrate Lyase antibody.

After reconstitution, the ATP Citrate Lyase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.