This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [RefSeq]

Optimal dilution of the GFAP antibody should be determined by the researcher.

A synthetic peptide specific to human GFAP was used as the immunogen for the GFAP antibody.

Store the GFAP antibody at -20oC.