The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. [RefSeq]

Optimal dilution of the CD63 antibody should be determined by the researcher.

A synthetic peptide specific to human CD63 was used as the immunogen for the CD63 antibody.

Store the CD63 antibody at -20oC.