The ACADM gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [RefSeq]

Optimal dilution of the Mcad antibody should be determined by the researcher.

A synthetic peptide specific to human Mcad / ACADM was used as the immunogen for the Mcad antibody.

Store the Mcad antibody at -20oC.