The protein encoded by this gene is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes. A processed pseudogene of ESRRA is located on chromosome 13q12.1. Alternatively spliced transcript variants have been found for this gene. [RefSeq]

Optimal dilution of the ESRRA antibody should be determined by the researcher.

A synthetic peptide specific to human ESRRA / Estrogen-related receptor alpha was used as the immunogen for the ESRRA antibody.

Store the ESRRA antibody at -20oC.