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主营:肿瘤,肿瘤生物标志物,细胞凋亡,免疫学,细胞生物学和转录因子
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当前位置: 首页 > 产品中心 > monoclonal_antibody > NSJ Bio/Thymidylate Synthase Antibody [clone ADAA-20] (RQ5083)/100 ul/RQ5083
商品详细NSJ Bio/Thymidylate Synthase Antibody [clone ADAA-20] (RQ5083)/100 ul/RQ5083
NSJ Bio/Thymidylate Synthase Antibody [clone ADAA-20] (RQ5083)/100 ul/RQ5083
NSJ Bio/Thymidylate Synthase Antibody [clone ADAA-20] (RQ5083)/100 ul/RQ5083
商品编号: RQ5083
品牌: NSJBioreagents
市场价: ¥8380.00
美元价: 6704.00
产地: 美国(厂家直采)
公司:
产品分类: 单克隆抗体
公司分类: monoclonal_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description

Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using, 10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occurring antisense transcript, mitochondrial enolase superfamily member 1, vary inversely when cell-growth progresses from late-log to plateau phase. Polymorphisms in this gene may be associated with etiology of neoplasia, including breast cancer, and response to chemotherapy. [RefSeq]

Application Notes

Optimal dilution of the Thymidylate Synthase antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human Thymidylate Synthase / TYMS was used as the immunogen for the Thymidylate Synthase antibody.

Storage

Store the Thymidylate Synthase antibody at -20oC.

品牌介绍
NSJ Bioreagents已有20多年的历史。 NSJ Bio提供领先的、广泛使用的单克隆抗体以及单克隆和多克隆抗体的所有领域的研究,包括肿瘤,肿瘤生物标志物,细胞凋亡,免疫学,细胞生物学和转录因子。产品提供多种规格,以更好地适应研究人员的测试需求和预算限制。   链接:http://www.nsjbio.com/ 温馨提示:不可用于临床治疗。 风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。