The APOB gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 (~240 kDa) and apoB-100 (~516 kDa): the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. [RefSeq]

Optimal dilution of the Apolipoprotein B antibody should be determined by the researcher.

A synthetic peptide specific to human Apolipoprotein B / APOB was used as the immunogen for the Apolipoprotein B antibody.

Store the Apolipoprotein B antibody at -20oC.