This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. [RefSeq]

Optimal dilution of the M6PR antibody should be determined by the researcher.

A synthetic peptide specific to human M6PR / IGF2R was used as the immunogen for the M6PR antibody.

Store the M6PR antibody at -20oC.