Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H+ currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc. [UniProt]

Optimal dilution of the CYBB antibody should be determined by the researcher.

A synthetic peptide specific to human Nox2 / CYBB was used as the immunogen for the CYBB antibody.

Store the CYBB antibody at -20oC.