This gene encodes a member of the acyl-CoA thioesterasefamily which catalyse the conversion of activated fatty acids tothe corresponding non-esterified fatty acid and coenzyme A.Expression of a mouse homolog in brown adipose tissue is induced bylow temperatures and repressed by warm temperatures. Higher levelsof expression of the mouse homolog has been found inobesity-resistant mice compared with obesity-prone mice, suggestinga role of acyl-CoA thioesterase 11 in obesity. Alternative splicingresults in transcript variants.
Titration of the ACOT11 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 549-575 from the human protein was used as the immunogen for this ACOT11 antibody.
Aliquot the ACOT11 antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.
