AKT2 is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.

Titration of the anti-AKT2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

This anti-AKT2 antibody was produced from a mouse immunized with AKT2 recombinant protein.

Aliquot the anti-AKT2 antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.