This gene encodes a member of the membrane-spanning 4Agene family. Members of this nascent protein family arecharacterized by common structural features and similar intron/exonsplice boundaries and display unique expression patterns amonghematopoietic cells and nonlymphoid tissues. This gene encodes aB-lymphocyte surface molecule which plays a role in the developmentand differentiation of B-cells into plasma cells. This familymember is localized to 11q12, among a cluster of family members.Alternative splicing of this gene results in two transcriptvariants which encode the same protein.

Titration of the anti-CD20 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

A portion of amino acids 266-294 from the human protein was used as the immunogen for this anti-CD20 antibody.

Aliquot the anti-CD20 antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.