MYC is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of the gene encoding MYC have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma.
Titration of the anti-Myc antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 40-69 from the human protein was used as the immunogen for this anti-Myc antibody.
Aliquot the anti-Myc antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.
