Myeloperoxidase (MPO) is a heme protein synthesized duringmyeloid differentiation that constitutes the major component ofneutrophil azurophilic granules. Produced as a single chainprecursor, myeloperoxidase is subsequently cleaved into a light andheavy chain.The mature myeloperoxidase is a tetramer composed of2 light chains and 2 heavy chains. This enzyme produces hypohalousacids central to the microbicidal activity of netrophils. [providedby RefSeq].

Titration of the anti-Myeloperoxidase antibody may be required due to differences in protocols and secondary/substrate sensitivity.

A portion of amino acids 420-448 from the human protein was used as the immunogen for this anti-Myeloperoxidase antibody.

Aliquot the anti-Myeloperoxidase antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.