Aquaporins are a family of small integral membraneproteins related to the major intrinsic protein (MIP or AQP0). Thisgene encodes an aquaporin which functions as a molecular waterchannel protein. It is a homotetramer with 6 bilayer spanningdomains and N-glycosylation sites. The protein physically resembleschannel proteins and is abundant in erythrocytes and renal tubes.The gene encoding this aquaporin is a possible candidate fordisorders involving imbalance in ocular fluid movement. Severaltranscript variants encoding different isoforms have been found forthis gene.
Titration of the AQP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 241-269 from the human protein was used as the immunogen for this AQP1 antibody.
Aliquot the AQP1 antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.
