Aquaporin 3 is a water channel protein. Aquaporins are afamily of small integral membrane proteins related to the majorintrinsic protein (MIP or AQP0). Aquaporin 3 is localized at thebasal lateral membranes of collecting duct cells in the kidney. Inaddition to its water channel function, aquaporin 3 has been foundto facilitate the transport of nonionic small solutes such as ureaand glycerol, but to a smaller degree. It has been suggested thatwater channels can be functionally heterogeneous and possess waterand solute permeation mechanisms.
Titration of the AQP3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 163-191 from the human protein was used as the immunogen for this AQP3 antibody.
Aliquot the AQP3 antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.
