ACCN2 / ASIC1 is a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a largeextracellular loop, which has many cysteine residues with conserved spacing. The member is expressed in most if not all brain neurons, and it may be an ion channel subunit; however, its function as an ion channel remains unknown.

Titration of the ASIC1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

A portion of amino acids 500-526 from the human protein was used as the immunogen for this ASIC1 antibody.

Aliquot the ASIC1 antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.