The protein encoded by this gene catalyzes the penultimatestep of the arginine biosynthetic pathway. There are approximately10 to 14 copies of this gene including the pseudogenes scatteredacross the human genome, among which the one located on chromosome9 appears to be the only functional gene for argininosuccinatesynthetase. Mutations in the chromosome 9 copy of ASS causecitrullinemia. Two transcript variants encoding the same proteinhave been found for this gene.
Titration of the ASS1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 281-310 from the human protein was used as the immunogen for this ASS1 antibody.
Aliquot the ASS1 antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.
