This gene encodes one of two cannabinoid receptors. Thecannabinoids, principally delta-9-tetrahydrocannabinol andsynthetic analogs, are psychoactive ingredients of marijuana. Thecannabinoid receptors are members of the guanine-nucleotide-bindingprotein (G-protein) coupled receptor family, which inhibitadenylate cyclase activity in a dose-dependent, stereoselective andpertussis toxin-sensitive manner. The two receptors have been foundto be involved in the cannabinoid-induced CNS effects (includingalterations in mood and cognition) experienced by users ofmarijuana. Multiple transcript variants encoding two differentprotein isoforms have been described for this gene. [provided byRefSeq].

Titration of the Cannabinoid Receptor 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

A portion of amino acids 161-187 from the human protein was used as the immunogen for this Cannabinoid Receptor 1 antibody.

Aliquot the Cannabinoid Receptor 1 antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.