
This gene is one of several cytokine genes clustered onthe q-arm of chromosome 17. Cytokines are a family of secretedproteins involved in immunoregulatory and inflammatory processes.This protein is CCL4 which inhibits HIV entry by bindingto the cellular receptor CCR5. The copy number of this gene variesamong individuals; most individuals have 1-5 copies in the diploidgenome, although rare individuals do not contain this gene at all.The human genome reference assembly contains two copies of thisgene. This record represents the more centromeric gene. [providedby RefSeq].
Titration of the CCL4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 22-48 from the human protein was used as the immunogen for this CCL4 antibody.
Aliquot the CCL4 antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.