Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers. [UniProt]

Titration of the CD10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

A portion of amino acids 272-300 from the human protein was used as the immunogen for this CD10 antibody.

Aliquot the CD10 antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.