CD11c, also known as Integrin alpha X (complement component 3 receptor 4 subunit) (ITGAX), is a type I transmembrane protein found at high levels on most human dendritic cells, but also on monocytes, macrophages, neutrophils, and some B cells that induces cellular activation and helps trigger neutrophil respiratory burst; expressed in hairy cell leukemias, acute non-lymphocytic leukemias, and some B-cell chronic lymphocytic leukemias.

The concentration stated for each application is a general starting point.Variations in protocols, secondaries and substrates may require the CD11c antibody to be titered up or down for optimal performance.

Human monocytic U937 phorbol ester-treated cells were used as the immunogen for this CD11c antibody.

Store the CD11c antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).