Recognizes a glycoprotein of 110kDa, identified as CD26. It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection.

Optimal dilution of the CD26 antibody should be determined by the researcher.

A synthetic peptide from the amino terminal region of the human protein was used as the immunogen for the CD26 antibody.

Store the CD26 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).