Cell division cycle 5-like protein, also called PCDC5RP or CDC5-like, is a protein that in humans is encoded by the CDC5L gene. The gene was mapped to chromosome 6p21 by fluorescence in situ hybridization. This DNA-binding protein involved in cell cycle control. It may act as a transcription activator. The Component of the PRP19-CDC5L complex forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The role of CDC5 in regulating Rho1 is likely to be relevant to cytokinesis and asymmetric cell division in other organisms.
The stated application concentrations are suggested starting amounts.Titration of the CDC5L antibody may be required due to differences in protocols and secondary/substrate sensitivity.
An amino acid sequence from the C-terminus of human Cell division cycle 5-like protein (KELQHRYADLLLEKETLKSKF) was used as the immunogen for this CDC5L antibody.
After reconstitution, the CDC5L antibody can be stored for up to one month at4oC.For long-term, aliquot and store at -20oC.Avoid repeated freezing and thawing.
