CDK-activating kinases (CAKs) are multisubunit proteins that phosphorylate and thus activate certain cyclin-dependent protein kinases in the regulation of cell cycle progression.The Cyclin dependent kinase7 gene is mapped to chromosome 2p15-cen. Cdk7 functions in both cyclin binding and T-loop phosphorylation and that these 2 steps of Cdk1 activation are mutually dependent.

The stated application concentrations are suggested starting amounts.Titration of the Cdk7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Recombinant human protein was used as the immunogen for this Cdk7 antibody.

After reconstitution, the Cdk7 antibody can be stored for up to one month at4oC.For long-term, aliquot and store at -20oC.Avoid repeated freezing and thawing.