Fractalkine is a transmembrane protein and chemokineinvolved in the adhesion and migration of leukocytes. The proteinencoded by this gene is a receptor for fractalkine. The encodedprotein also is a coreceptor for HIV-1, and some variations in thisgene lead to increased susceptibility to HIV-1 infection and rapidprogression to AIDS. Four transcript variants encoding twodifferent isoforms have been found for this gene. [provided byRefSeq].

Titration of the CX3CR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

A portion of amino acids 40-69 from the human protein was used as the immunogen for this CX3CR1 antibody.

Aliquot the CX3CR1 antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.