Anhidrotic ectodermal dysplasia is an X-linked recessive disorder which affects ectodermal structures. Ectodysplasin-A, the protein encoded by the EDA gene, is a member of the tumor necrosis factor ligand superfamily that forms a collagen triple helix, suggesting functions in signal transduction and cell adhesion. Wnt signaling controls EDA gene expression, but Ectodysplasin-A does not feedback on the Wnt pathway.

The stated application concentrations are suggested starting amounts.Titration of the EDA antibody may be required due to differences in protocols and secondary/substrate sensitivity.

An amino acid sequence from the middle region of human EDA (HLQGQGSAIQVKNDLS) was used as the immunogen for this EDA antibody (100% homologous in human, mouse and rat).

After reconstitution, the EDA antibody can be stored for up to one month at4oC.For long-term, aliquot and store at -20oC.Avoid repeated freezing and thawing.