
The epidermal growth factor receptor is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer.
Titration of the EGF Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 1048-1077 from the human protein was used as the immunogen for this EGF Receptor antibody.
Aliquot the EGF Receptor antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.