May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.

Titration of the Ep-CAM antibody may be required due to differences in protocols and secondary/substrate sensitivity.

This Ep-CAM antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 299-334 amino acids from the C-terminal region of the human protein.

Aliquot the Ep-CAM antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.