Implicated in the control of cell growth. Plays a role in the regulation of intracellular calcium levels, with isoform 2 showing the greater ability to mobilize cytoplasmic calcium in comparison to isoform 1. Required in brain development and mature brain function with important roles in the regulation of axon growth, axon guidance, and neurite extension. Blocks axon outgrowth and attraction induced by NTN1 by phosphorylating its receptor DDC.
Titration of the Fyn antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 507-535 from the mouse protein was used as the immunogen for this Fyn antibody.
Aliquot the Fyn antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.
